Comprehensive Characterization Services

• Bioscience Product Characterization Services - Structural and Physicochemical Characterization
• Biosimilars - Testing, characterization, and comparison services
• Biopharmaceuticals - Structural and physicochemical protein characterization
• Protein Characterization Services
• Instrumentation & Methodologies

Analytical Services in Biopharmaceuticals

• Glycoprotein/Recombinant Proteins
• PEGylated Proteins
• Biosimilars
• Vaccines
• Therapeutic Enzymes
• Peptides
• Antibody Drug Conjugates (ADC)
• Antibodies
• Monoclonal Antibodies
• Bispecific Antibodies
• Fab Fragments
• Fusion Proteins

Protein Identification & Characterization

Primary Structure Analysis

Amino Acid Analysis (AAA), N-terminal and C-terminal sequencing, De novo sequencing, Peptide mapping, Disulfide bridge, Intact molecular weight.

Post Translational Modification (PTM) Analysis

Glycosylation and Glycan characterization, N-linked glycosylation, O-linked glycosylation, site occupancy, post-translational modifications.

Secondary and Tertiary Structure Analysis

Circular Dichroism (CD), Fluorescence Spectroscopy (Intrinsic and Extrinsic), Fourier Transform InfraRed (FT-IR).

Structural Stability and Aggregation Analysis

Differential Scanning Calorimetry (DSC), Dynamic Light Scattering (DLS), Size Exclusion Chromatography with Multi-Angle Light Scattering (SEC-MALS), Sedimentation Velocity Analytical Ultracentrifugation (SV-AUC).